Chemotherapy
compute_cell_death_rate_for_chemo(t, chemo_spec)
Compute the rate of cell death induced by chemotherapy at a given time.
Parameters:
| Name | Type | Description | Default |
|---|---|---|---|
t
|
datetime
|
The current time for the calculation. |
required |
chemo_spec
|
ChemotherapySpecification
|
Specifications for chemotherapy, including sensitivity and protocol. |
required |
Returns:
| Name | Type | Description |
|---|---|---|
float |
Tensor
|
The rate of cell death induced by the drug. |
compute_chemo_concentration_for_dose(t, decay_rate, treatment_day, dose)
Compute the drug concentration for a single chemotherapy dose.
This uses an exponential decay model to calculate the concentration of the drug at a specific time after its administration.
Parameters:
| Name | Type | Description | Default |
|---|---|---|---|
t
|
datetime
|
The current time for concentration calculation. |
required |
decay_rate
|
float
|
The drug decay rate (1/day). |
required |
treatment_day
|
TreatmentTime
|
The time the dose was administered. |
required |
dose
|
float
|
The administered dose. |
required |
Returns:
| Name | Type | Description |
|---|---|---|
float |
float
|
The drug concentration at time |
compute_chemo_concentrations(t, chemotherapy_specification)
Compute the concentrations of chemotherapy drugs for all doses in a protocol.
Parameters:
| Name | Type | Description | Default |
|---|---|---|---|
t
|
datetime
|
The current time for concentration calculation. |
required |
chemotherapy_specification
|
ChemotherapySpecification
|
Specifications for chemotherapy, including protocol and decay rate. |
required |
Returns:
| Type | Description |
|---|---|
List[float]
|
List[float]: A list of drug concentrations, one for each dose in the protocol. |
compute_total_cell_death_chemo(t, chemo_specs)
Compute the total rate of cell death induced by multiple chemotherapy drugs.
Parameters:
| Name | Type | Description | Default |
|---|---|---|---|
t
|
datetime
|
The current time for the calculation. |
required |
chemo_specs
|
List[ChemotherapySpecification]
|
A list of chemotherapy specifications for different drugs. |
required |
Returns:
| Name | Type | Description |
|---|---|---|
float |
Tensor
|
The total rate of cell death induced by all drugs. |
plot_chemotherapy(timesteps, chemotherapy_specifications)
Plot chemotherapy drug concentrations and their effects over time.
This function visualizes the time-dependent concentrations of chemotherapy drugs and their sensitivity-scaled effects, as well as the total cell death rate.
Parameters:
| Name | Type | Description | Default |
|---|---|---|---|
timesteps
|
List[datetime]
|
The times at which to compute the concentrations and effects. |
required |
chemotherapy_specifications
|
List[ChemotherapySpecification]
|
Specifications for the chemotherapy drugs to be plotted. |
required |